Australian scientists have found an exciting discovery that could dramatically improve the treatment of chronic injuries and diseases such as diabetes. Researchers from the South Australian Health and Medical Research Institute (SAHMRI) and the University of Adelaide have discovered a previously unknown cell type called “EndoMac progenitor cells,” which could unlock novel healing mechanisms in animals.
This discovery follows nine years of significant investigation.
EndoMac progenitor cells, discovered in the outer layer of adult mice’s aortas, have the unusual capacity to differentiate into two critical cell types: endothelial cells, which produce blood vessels, and macrophages, which play an important role in the repair of tissues. Dr. Sanuri Liyanage, one of the project’s primary experts, noted that these cells activate in reaction to injury or insufficient blood supply, allowing the body to recuperate more effectively.
These cells are distinguished by their low susceptibility to immune system attack, as they do not display normal “self” signals, making them suitable candidates for stem cell therapy.
In diabetic animal models, transplanting EndoMac cells resulted in considerable improvements in wound healing. This discovery has the potential to revolutionise regenerative medicine by providing novel treatments for people with chronic wounds that do not heal naturally.
