The recent study shows that the level of antibody present in infected patients is much higher after the single dose of the Sputnik V Covid vaccine as compared to participants with no history of infection.
As per the News Asia One, Sputnik V vaccine is produced using the combination of two adenoviruses. Adenoviruses are common viruses that can cause a realm of illness with symptoms like fever, sore throat, and cold. Sputnik V’s two doses are 92% effective against covid-19 infection.
On 289 health workers a research was carried out on one and two shots in Argentina. All the volunteers after three weeks of the second dose generated virus-specific immunoglobulin G (IgG) antibodies with no prior infection. It is the most common type of antibody found in the blood. However, 94% of volunteers after receiving their first dose developed IgG antibodies against the virus. Whereas 90% of the volunteers showed neutralizing antibodies which directly interferes with the capability of viruses to infect cells. After a single dose, the high antibody level in naive participants suggests the benefit of delaying the second dose.
For the previously infected volunteers, the second dose does not increase the production of neutralizing antibodies.