An AI tool developed at IIT Madras maps cancer-causing genes

An AI tool developed at IIT Madras maps cancer-causing genes

On Wednesday, the researcher at the Indian Institute of Technology, Madras developed an Artificial Intelligence-based tool- PIVOT that can detect cancer-causing genes in individuals. As per WTO, cancer is one of the main causes of death worldwide.

According to the institute, this tool will be beneficial for the strategic treatment of cancer which will predict genes that are responsible for causing it, and details are published in a peer-reviewed journal ‘Frontier in Genetics’.

The statement read, “The prediction is based on a model that utilizes information on mutation, expression of genes, and copy number variation in genes and perturbations in the biological network due to an altered gene expression”.

IIT-Madras Dean (Global Engagement) Raghunathan Rengaswamy, and Professor Karthik Raman, both affiliated with the Bhupat and Jyoti Mehta School of Biosciences, and members of the Robert Bosch Centre for Data Science and Artificial Intelligence (RBCDSAI) led the research project. Researcher Malvika Sudhakar was also affiliated with the IIT-Madras.

Core member of RBCDSAI, IIT Madras Dr. Karthik Raman said, “Cancer is a complex disease which does not support one treatment. These models that help in pinpointing differences between patients are very useful as cancer treatment increasingly moves toward personalised medicine